Joyce Y. Guo

Joyce Y. Guo, PhD

Post-doctoral Researcher
Google Scholar profile

My main research interest is to explore if there is a progressive structural and functional deterioration during the course of psychosis using longitudinal design, and the long-term effects of current antipsychotic medications on the neural system. I am also interested in sex dimorphisms in psychosis that may lead to inventing gender-based novel treatments.


J Guo, H Wange, T Lesh, D Mathalon, R Loewy, C Carter, TA Niendam Altered Cognitive Control-Related Brain Activity and Functional Connectivity in First-Episode Schizophrenia & Clinical-High-Risk Youth Biological Psychiatry 2020.

JY Guo, TA Lesh, TA Niendam, JD Ragland, LM Tully, CS Carter. Brain free water alterations in first-episode psychosis: a longitudinal analysis of diagnosis, course of illness, and medication effects. Psychological Medicine 2020.

D Bergé, A Mané, TA Lesh, ..., Joyce Y Guo, et al. Elevated Extracellular Free-Water in a Multicentric First-Episode Psychosis Sample, Decrease During the First 2 Years of Illness Schizophrenia Bulletin 2020.

JY Guo, John D Ragland, Cameron S Carter. Memory and cognition in schizophrenia. Molecular Psychiatry 2019.

Joyce Y Guo, Tara A Niendam, Andrea M Auther, Ricardo E Carrión, Barbara A Cornblatt, J Daniel Ragland, Steven Adelsheim, Roderick Calkins, Tamara G Sale, Stephan F Taylor, William R McFarlane, Cameron S Carter Predicting psychosis risk using a specific measure of cognitive control: a 12-month longitudinal study. Psychological Medicine 2019.

Guo JY, Isohanni M, Miettunen J, et al. Brain structural changes in women and men during midlife. Neuroscience Letters. 2016.

Guo, J.Y., Huhtaniska, S., Miettunen, J., Jaaskelainen, E., Kiviniemi, V., Nikkinen, J., Moilanen, J., Haapea, M., Maki, P., Jones, P.B., Veijola, J., Isohanni, M., Murray, G.K. Longitudinal regional brain volume loss in schizophrenia: Relationship to antipsychotic medication and change in social function. Schizophr Res. 2015.

Veijola J, Guo JY, Moilanen J, Jääskeläinen E, Miettunen J, Kyllonen M, Haapea M, Huhtaniska S, Alaraisanen A, Maki P, Starck T, Kiviniemi V, Nikkinen J, Remes J, Tanskanen P, Tervonen O, Wink MA, Barnes A, Kehagia A, Suckling J, Kobayashi H, Barnett J, Koponen H, Jones P, Isohanni M, Murray G. Longitudinal changes in total brain volume in schizophrenia: relation to symptom severity, cognition and antipsychotic medication. PLoS One 2014.